Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.61 |
| ▸ | TOP2A | P11388 | 2/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.52 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.52 |
| ▸ | USP7 | Q93009 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GLI1 | P08151 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14350531 | 0.86 | PTPN1 (0.65) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL851609 | 0.86 | PTPN1 (0.65) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL18100185 | 0.86 | PTPN1 (0.65) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL19338218 | 0.85 | PTPN1 (0.57) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL23766687 | 0.85 | PTPN1 (0.57) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL18690037 | 0.84 | PTPN1 (0.60) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL18688190 | 0.84 | PTPN1 (0.60) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL13359971 | 0.84 | PTPN1 (0.60) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL13165682 | 0.83 | SLC10A1 (0.65) | PTPN1TOP2ACES2CES1GPBAR1 | |
| SCHEMBL19452474 | 0.83 | SLC10A1 (0.65) | PTPN1TOP2ACES2CES1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110159120-A1 | SYNERGISTIC ANTI-INFLAMMATORY COMPOSITIONS COMPRISING BOSWELLIA SERRATA EXTRACTS | LAILA NUTRACEUTICALS (IN) | 2011-06-30 | — | — | US | disclosed |
| US-20080167254-A1 | TRITERPENES DERIVATIVES AND USES THEREOF AS ANTITUMOR AGENTS OR ANTI-INFLAMMATORY AGENTS | UNIVERSITE DU QUEBEC A CHICOUTIMI (CA) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167254-A1 | TRITERPENES DERIVATIVES AND USES THEREOF AS ANTITUMOR AGENTS OR ANTI-INFLAMMATORY AGENTS | TNF, B3GAT3, ST3GAL3 | PTPN1 2782/4885TOP2A 1859/4885CES2 1567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.