Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.45 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863076 | 0.97 | TLR7 (0.53) | TLR7TLR8TDP1GBA1NUDT1 | |
| Trifluoroacetic Acid SCHEMBL4864753 | 0.94 | TLR7 (0.51) | TLR7TLR8TDP1GBA1NUDT1 | |
| SCHEMBL4871874 | 0.89 | TLR7 (0.55) | TLR7TLR8TDP1 | |
| SCHEMBL3863594 | 0.88 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL4872671 | 0.85 | TLR7 (0.48) | TLR7TLR8NUDT1 | |
| SCHEMBL3867295 | 0.82 | SLC6A4 (0.51) | TDP1GBA1PDE6DSLC6A4ADORA2A | |
| SCHEMBL13837300 | 0.81 | TLR7 (0.71) | TLR7TLR8 | |
| SCHEMBL3864917 | 0.81 | TDP1 (0.53) | TDP1GBA1PDE6DSLC6A4RNF168 | |
| SCHEMBL3864057 | 0.81 | TLR7 (0.55) | TLR7TLR8 | |
| SCHEMBL5617098 | 0.80 | TLR7 (0.67) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110142874-A1 | Compositions, Methods, and Kits for Eliciting an Immune Response | ARIZONA BOARD OF REGENTS (US) | 2011-06-16 | — | — | US | disclosed |