Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.72 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.72 |
| ▸ | STK4 | Q13043 | 5/20 | 0.68 |
| ▸ | STK25 | O00506 | 1/20 | 0.68 |
| ▸ | CIT | O14578 | 1/20 | 0.68 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.68 |
| ▸ | GAK | O14976 | 1/20 | 0.68 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.68 |
| ▸ | JAK2 | O60674 | 1/20 | 0.68 |
| ▸ | STK17B | O94768 | 1/20 | 0.68 |
| ▸ | STK10 | O94804 | 1/20 | 0.68 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.68 |
| ▸ | ABL1 | P00519 | 1/20 | 0.68 |
| ▸ | LCK | P06239 | 1/20 | 0.68 |
| ▸ | FYN | P06241 | 1/20 | 0.68 |
| ▸ | FES | P07332 | 1/20 | 0.68 |
| ▸ | CSF1R | P07333 | 1/20 | 0.68 |
| ▸ | YES1 | P07947 | 1/20 | 0.68 |
| ▸ | LYN | P07948 | 1/20 | 0.68 |
| ▸ | MET | P08581 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2027968 | 0.92 | EGFR (0.86) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL10108217 | 0.89 | EGFR (0.85) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL9911364 | 0.85 | EGFR (0.65) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL9911505 | 0.84 | EGFR (0.64) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL5496335 | 0.84 | EGFR (1.00) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL5496337 | 0.84 | EGFR (1.00) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL12094780 | 0.83 | EGFR (0.63) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL14925319 | 0.82 | EGFR (1.00) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL5499556 | 0.82 | EGFR (0.86) | EGFRERBB2STK4STK25CIT | |
| SCHEMBL6466768 | 0.82 | EGFR (0.86) | EGFRERBB2STK4STK25CIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011077095-A1 | QUINOLINE DERIVATIVES USED AS PET IMAGING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |