Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 17/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035859 | 0.91 | EIF2AK4 (0.46) | EIF2AK4FLT3 | |
| SCHEMBL2035861 | 0.91 | EIF2AK4 (0.46) | EIF2AK4FLT3 | |
| SCHEMBL12643715 | 0.89 | EIF2AK4 (0.40) | EIF2AK4JAK2JAK1JAK3FLT3 | |
| SCHEMBL12614643 | 0.85 | EIF2AK4 (0.47) | EIF2AK4JAK2JAK1JAK3FLT3 | |
| SCHEMBL12643893 | 0.84 | EIF2AK4 (0.43) | EIF2AK4FLT3 | |
| SCHEMBL12643822 | 0.84 | EIF2AK4 (0.44) | EIF2AK4JAK2JAK1JAK3FLT3 | |
| SCHEMBL2036807 | 0.83 | EIF2AK4 (0.47) | EIF2AK4JAK2JAK1JAK3FLT3 | |
| SCHEMBL2000295 | 0.83 | EIF2AK4 (0.47) | EIF2AK4 | |
| SCHEMBL2000293 | 0.83 | EIF2AK4 (0.47) | EIF2AK4 | |
| SCHEMBL12643884 | 0.83 | EIF2AK4 (0.41) | EIF2AK4JAK2JAK1JAK3FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076419-A1 | IMIDAZOPYRIDINE DERIVATIVES AS JAK INHIBITORS | ALMIRALL, S.A. (ES) | 2011-06-30 | — | — | WO | disclosed |