Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 8/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028474 | 0.92 | CSNK2B (0.43) | TYK2CSNK2BCDK2CDK9KDM4E | |
| SCHEMBL2029617 | 0.79 | CSNK2B (0.48) | TYK2CSNK2BKDM4ENPC1RAB9A | |
| SCHEMBL12587708 | 0.79 | CSNK2B (0.48) | TYK2CSNK2BKDM4ENPC1RAB9A | |
| SCHEMBL2029618 | 0.79 | CSNK2B (0.48) | TYK2CSNK2BKDM4ENPC1RAB9A | |
| SCHEMBL2028002 | 0.75 | MAPKAPK2 (0.43) | TYK2CDK2CDK9KDM4ENPC1 | |
| SCHEMBL1487862 | 0.68 | CSNK2B (0.62) | TYK2CSNK2BCDK2CSNK2A2KCNH2 | |
| SCHEMBL12841015 | 0.68 | CSNK2B (0.61) | TYK2CSNK2BCDK2CSNK2A2KCNH2 | |
| SCHEMBL1528130 | 0.67 | CSNK2B (0.60) | TYK2CSNK2BCDK2CSNK2A2KCNH2 | |
| SCHEMBL12841018 | 0.66 | CSNK2B (0.44) | TYK2CSNK2BCDK2CSNK2A2KCNH2 | |
| SCHEMBL23903267 | 0.66 | KCNH2 (0.46) | TYK2CSNK2BCDK2CSNK2A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152240-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152240-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CDK2, CKS2, CSNK2A1 | TYK2 63/4885CSNK2B 13/4885CDK2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.