Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.38 |
| ▸ | HIPK1 | Q86Z02 | 2/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.38 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12645430 | 0.92 | CSNK2B (0.43) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL2028606 | 0.91 | CSNK2B (0.47) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL2028604 | 0.91 | CSNK2B (0.47) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL12645888 | 0.88 | CSNK2B (0.42) | CSNK2BCSNK2A1CSNK2A2LMNAGSK3B | |
| SCHEMBL12645435 | 0.87 | CSNK2B (0.45) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL2028544 | 0.86 | CSNK2B (0.48) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL2028547 | 0.86 | CSNK2B (0.48) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL12644987 | 0.85 | CSNK2B (0.44) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 | |
| SCHEMBL12645171 | 0.84 | CSNK2B (0.50) | CSNK2BKCNH2CSNK2A1CSNK2A2TYK2 | |
| SCHEMBL12645140 | 0.84 | CSNK2B (0.47) | CSNK2BKCNH2CSNK2A1CSNK2A2HIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9303033-B2 | Pyrazolopyrimidines and related heterocycles as CK2 inhibitors | SENHWA BIOSCIENCES, INC. (TW) | 2016-04-05 | — | — | US | disclosed |
| US-8575177-B2 | Pyrazolopyrimidines and related heterocycles as CK2 inhibitors | SENHWA BIOSCIENCES, INC. (TW) | 2013-11-05 | — | — | US | disclosed |
| US-20110152240-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152240-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CDK2, CKS2, CSNK2A1 | CSNK2B 13/4885KCNH2 1774/4885CSNK2A1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.