SCHEMBL12646355

SCHEMBL12646355

CCc1ccc(Cc2c(O[C@@H]3O[C@H](COC(=O)CO)[C@@H](O)[C@H](O)[C@H]3O)nn(C3CCC3)c2C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.49
SLC5A1 P13866 17/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3772852 0.91 SLC5A2 (0.50) SLC5A2SLC5A1
SCHEMBL3775262 0.91 SLC5A2 (0.56) SLC5A2SLC5A1
SCHEMBL797556 0.91 SLC5A2 (0.50) SLC5A2SLC5A1
SCHEMBL797496 0.90 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL796791 0.89 SLC5A2 (0.62) SLC5A2SLC5A1
SCHEMBL3766942 0.89 SLC5A2 (0.62) SLC5A2SLC5A1
SCHEMBL12588984 0.88 SLC5A2 (0.61) SLC5A2SLC5A1
SCHEMBL13446116 0.85 SLC5A2 (0.50) SLC5A2SLC5A1
SCHEMBL12646410 0.85 SLC5A2 (0.50) SLC5A2SLC5A1
SCHEMBL12646294 0.84 SLC5A2 (0.49) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7956041-B2 antidiabetic mixture contains an inhibitor of renal glucose reabsorption and a hypoglycemic agent; controlling blood glucose level; tolbutamide, chlorpropamide, glibenclamide, glipizide, glimepiride, and gliclazide; metformin, phenformin and buformin; repaglinide, nateglinide and mitiglinide AJINOMOTO CO., INC. (JP) 2011-06-07 US disclosed