Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 5/20 | 0.78 |
| ▸ | KIT | P10721 | 4/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | MET | P08581 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1267073 | 0.91 | CSF1R (0.78) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL878907 | 0.91 | CSF1R (0.78) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL12926432 | 0.90 | CSF1R (0.71) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL1267837 | 0.89 | CSF1R (0.75) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL1267581 | 0.89 | CSF1R (0.75) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL19898655 | 0.88 | CSF1R (0.74) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL29431664 | 0.88 | CSF1R (1.00) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL1268018 | 0.88 | CSF1R (1.00) | CSF1RKITCYP2C19CYP3A4MET | |
| SCHEMBL1267815 | 0.87 | CSF1R (0.73) | CSF1RKITCYP2C19CYP3A4MET | |
| Hydrochloric Acid SCHEMBL20166201 | 0.87 | CSF1R (0.98) | CSF1RKITCYP2C19CYP3A4MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947708-B2 | Compounds modulating C-kit activity | PLEXXIKON, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-20090105297-A1 | Compounds Modulating C-Kit Activity | PLEXXIKON INC | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105297-A1 | Compounds Modulating C-Kit Activity | KIT, CDC7, CDK7 | CSF1R 363/4885KIT 1/4885CYP2C19 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.