Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.59 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12355393 | 0.88 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL1798358 | 0.88 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1798353 | 0.88 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL1799970 | 0.87 | TRPV1 (0.65) | TRPV1ALOX5APFEN1 | |
| SCHEMBL1799973 | 0.87 | TRPV1 (0.65) | TRPV1ALOX5APFEN1 | |
| SCHEMBL1797132 | 0.86 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL1797129 | 0.86 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL1799896 | 0.85 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL1800629 | 0.85 | TRPV1 (0.53) | TRPV1ALOX5APFEN1 | |
| SCHEMBL1800628 | 0.85 | TRPV1 (0.53) | TRPV1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951829-B2 | Benzimidazole modulators of VR1 | JANSSEN PHARMACEUTICA NV (BE) | 2011-05-31 | — | — | US | disclosed |