Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12165098 | 0.85 | EHMT2 (0.45) | EHMT2MEN1KMT2AGAAMAPT | |
| SCHEMBL12165271 | 0.84 | EHMT2 (0.44) | EHMT2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12165073 | 0.84 | EHMT2 (0.45) | EHMT2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12165220 | 0.83 | EHMT2 (0.44) | EHMT2MEN1KMT2AGAAMAPT | |
| SCHEMBL12165326 | 0.83 | EHMT2 (0.46) | EHMT2CTSDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12165388 | 0.83 | EHMT2 (0.46) | EHMT2CTSDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12165300 | 0.83 | EHMT2 (0.44) | EHMT2MAPTKDM4ECTSDHPGD | |
| SCHEMBL12165224 | 0.83 | EHMT2 (0.46) | EHMT2CTSDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12165291 | 0.82 | EHMT2 (0.46) | EHMT2MEN1KMT2AGAAKDM4E | |
| SCHEMBL12165251 | 0.81 | EHMT2 (0.45) | EHMT2CTSDSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053697-A1 | 2-AMINOINDOLE COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA | GENZYME CORPORATION (US) | 2011-05-05 | — | — | WO | disclosed |