Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | F7 | P08709 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1818165 | 0.99 | TSHR (0.50) | TSHRF7F2F10SMN1; SMN2 | |
| SCHEMBL12655254 | 0.83 | TSHR (0.57) | TSHRSMN1; SMN2PYGLTRPV1MEN1 | |
| Hydrochloric Acid SCHEMBL1815094 | 0.83 | TSHR (0.54) | TSHRF7F2F10SMN1; SMN2 | |
| SCHEMBL4019644 | 0.82 | TSHR (0.57) | TSHRF7F2F10SMN1; SMN2 | |
| SCHEMBL24575982 | 0.82 | TSHR (0.71) | TSHRSMN1; SMN2TRPV1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28482311 | 0.81 | IDO1 (0.56) | TSHRF7F2F10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30496704 | 0.81 | IDO1 (0.56) | TSHRF7F2F10SMN1; SMN2 | |
| SCHEMBL24486730 | 0.79 | EPHX2 (0.67) | TSHRSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL12655527 | 0.78 | TSHR (0.55) | TSHRSMN1; SMN2PYGLTRPV1MEN1 | |
| SCHEMBL1817391 | 0.77 | TSHR (0.57) | TSHRSMN1; SMN2PYGLTRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060395-A1 | CYCLIC UREAS USEFUL AS HIV INHIBITORS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060394-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |