Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | WHR1 | P49842 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 3/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 7/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | GALR2 | O43603 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | RBP1 | P09455 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298156 | 0.89 | WHR1 (0.39) | KITAXLFLT3WHR1LRRK2 | |
| SCHEMBL12655398 | 0.82 | SRC (0.44) | KITAXLFLT3LRRK2JAK2 | |
| SCHEMBL1298776 | 0.80 | LRRK2 (0.47) | WHR1LRRK2SYKJAK2 | |
| SCHEMBL1298259 | 0.80 | LRRK2 (0.55) | LRRK2SYK | |
| SCHEMBL1297937 | 0.80 | KIT (0.57) | KITAXLFLT3SYKJAK2 | |
| SCHEMBL1298348 | 0.77 | LRRK2 (0.49) | WHR1LRRK2SYKJAK2 | |
| SCHEMBL1298858 | 0.75 | LRRK2 (0.53) | WHR1LRRK2SYKJAK2 | |
| SCHEMBL1298518 | 0.73 | LRRK2 (0.47) | WHR1BCL6LRRK2SYKJAK2 | |
| SCHEMBL1325426 | 0.72 | LRRK2 (0.47) | WHR1LRRK2SYKJAK2 | |
| SCHEMBL1298682 | 0.71 | LRRK2 (0.39) | BCL6LRRK2SYKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011053861-A1 | KINASE INHIBITORS | GENOSCO (US) | 2011-05-05 | — | — | WO | disclosed |