Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616138 | 0.69 | — | — | |
| SCHEMBL16257980 | 0.67 | TP53 (0.31) | TP53TSHR | |
| SCHEMBL23518933 | 0.61 | POLB (0.34) | — | |
| SCHEMBL13956997 | 0.60 | — | — | |
| SCHEMBL23640229 | 0.60 | — | — | |
| SCHEMBL24302268 | 0.60 | — | — | |
| SCHEMBL19441287 | 0.59 | — | — | |
| SCHEMBL12462736 | 0.59 | — | — | |
| SCHEMBL12582193 | 0.59 | — | — | |
| SCHEMBL14161113 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316829-A1 | Heterocyclic derivatives as modulators of ion channels | Vertex Pharmaceuticals Incorporated (US) | 2011-05-04 | — | — | EP | disclosed |
| EP-2308872-A1 | Heterocyclic derivatives as modulators of ion channels | Vertex Pharmaceuticals Incorporated (US) | 2011-04-13 | — | — | EP | disclosed |