Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862099 | 0.90 | TRPV1 (0.63) | TRPV1SCN9AMAPK3GPR52 | |
| SCHEMBL12666836 | 0.90 | TRPV1 (0.56) | TRPV1SCN9AMAPK3DYRK3GSK3A | |
| SCHEMBL12666699 | 0.90 | SCN9A (0.41) | TRPV1SCN9AGSK3AGSK3B | |
| SCHEMBL12666001 | 0.89 | TRPV1 (0.58) | TRPV1MAPK3DYRK3GSK3AGSK3B | |
| SCHEMBL12666695 | 0.87 | TRPV1 (0.54) | TRPV1MAPK3GPR52DYRK3GSK3A | |
| SCHEMBL12666840 | 0.86 | TRPV1 (0.55) | TRPV1MAPK3DYRK3GSK3AGSK3B | |
| SCHEMBL12666839 | 0.85 | TRPV1 (0.57) | TRPV1SCN9AMAPK3 | |
| SCHEMBL1858243 | 0.82 | TRPV1 (0.63) | TRPV1MAPK3GPR52DYRK3GSK3A | |
| SCHEMBL12665999 | 0.80 | TRPV1 (0.43) | TRPV1SCN9ADYRK3GSK3AGSK3B | |
| SCHEMBL12667077 | 0.80 | TRPV1 (0.56) | TRPV1SCN9AMAPK3GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935702-B2 | Substituted biaryl quinolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2011-05-03 | — | — | US | disclosed |