SCHEMBL12666949

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4254670	0.79	HDAC3 (0.91)	HDAC3GAAMEN1KMT2AALDH1A1
	SCHEMBL4373141	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL18825687	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL4369180	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL18825664	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL25222615	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL4382929	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL5634680	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL10353082	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A
	SCHEMBL18825661	0.79	GAA (0.59)	HPGDHDAC3GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.