Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12669715 | 0.92 | BRAF (0.44) | BRAFADRA1A | |
| SCHEMBL12670313 | 0.91 | BRAF (0.41) | BRAF | |
| SCHEMBL12668181 | 0.91 | BRAF (0.48) | BRAFADRA1A | |
| SCHEMBL9987746 | 0.85 | BRAF (0.51) | BRAFADRA1A | |
| SCHEMBL14866055 | 0.85 | BRAF (0.52) | BRAFADRA1A | |
| SCHEMBL12668225 | 0.85 | BRAF (0.68) | BRAF | |
| SCHEMBL9987067 | 0.85 | BRAF (0.55) | BRAFADRA1A | |
| SCHEMBL1872619 | 0.84 | BRAF (0.49) | BRAFADRA1A | |
| SCHEMBL1884234 | 0.84 | BRAF (0.48) | BRAF | |
| SCHEMBL9987787 | 0.84 | BRAF (0.49) | BRAFADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011059610-A1 | BENZENE SULFONAMIDE THIAZOLE AND OXAZOLE COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-05-19 | — | — | WO | disclosed |