Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377508 | 0.92 | PPARD (0.78) | PPARDPPARA | |
| SCHEMBL377469 | 0.92 | PPARD (0.78) | PPARDPPARA | |
| SCHEMBL13680160 | 0.92 | PPARD (0.81) | PPARDPPARA | |
| SCHEMBL377637 | 0.90 | PPARD (0.84) | PPARDPPARA | |
| SCHEMBL377636 | 0.90 | PPARD (0.84) | PPARDPPARA | |
| Seladelpar SCHEMBL390098 | 0.89 | PPARD (1.00) | PPARDPPARA | |
| Seladelpar SCHEMBL394392 | 0.89 | PPARD (1.00) | PPARDPPARA | |
| Seladelpar SCHEMBL29373526 | 0.89 | PPARD (1.00) | PPARDPPARA | |
| Seladelpar SCHEMBL392331 | 0.89 | PPARD (1.00) | PPARDPPARA | |
| SCHEMBL377627 | 0.89 | PPARD (0.83) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669288-B2 | Lysine salts of 4-((phenoxyalkyl)thio)-phenoxyacetic acid derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2014-03-11 | — | — | US | disclosed |
| US-20110105616-A1 | NOVEL LYSINE SALTS OF 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACID DERIVATIVES | CYMABAY THERAPEUTICS, INC. | 2011-05-05 | — | — | US | disclosed |
| US-20070060649-A1 | NOVEL LYSINE SALTS OF 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACID DERIVATIVES | CYMABAY THERAPEUTICS, INC. | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060649-A1 | NOVEL LYSINE SALTS OF 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACID DERIVATIVES | PPARA, PPARD, PPARG | PPARD 2/4885PPARA 1/4885 |
| US-20110105616-A1 | NOVEL LYSINE SALTS OF 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACID DERIVATIVES | PPARA, PPARD, PPARG | PPARD 2/4885PPARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.