SCHEMBL12673 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CARM1	Q86X55	1/20	0.41

▸	PRMT6	Q96LA8	1/20	0.41

▸	PRMT1	Q99873	1/20	0.41

▸	PRMT8	Q9NR22	1/20	0.41

▸	ACHE	P22303	3/20	0.36

▸	HRH3	Q9Y5N1	6/20	0.35

▸	SIGMAR1	Q99720	2/20	0.35

▸	POLB	P06746	1/20	0.34

▸	HTT	P42858	1/20	0.34

▸	KDM4E	B2RXH2	2/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12449708	1.00	CARM1 (0.41)	CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL12449704	1.00	CARM1 (0.41)	CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL12449687	0.91	CARM1 (0.45)	CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL12451	0.91	CARM1 (0.45)	CARM1PRMT6PRMT1PRMT8ACHE
SCHEMBL12449652	0.90	KDM4E (0.45)	HRH3POLBKDM4E
SCHEMBL12449651	0.90	KDM4E (0.45)	HRH3POLBKDM4E
SCHEMBL12774	0.90	KDM4E (0.45)	HRH3POLBKDM4E
SCHEMBL12775	0.90	KDM4E (0.45)	HRH3POLBKDM4E
SCHEMBL12522637	0.88	KDM4E (0.37)	CARM1PRMT6PRMT1PRMT8HRH3
SCHEMBL12449657	0.82	KDM4E (0.45)	HRH3POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2011058149-A1	TRICYCLIC PYRAZOL AMINE DERIVATIVES	MERCK SERONO S.A. (CH)	2011-05-19	—	—	WO	disclosed