Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268359 | 0.77 | SLC5A1 (0.32) | SLC5A1SLC5A2 | |
| SCHEMBL9049283 | 0.74 | — | — | |
| SCHEMBL9789419 | 0.74 | — | — | |
| SCHEMBL9049291 | 0.74 | — | — | |
| SCHEMBL1267454 | 0.74 | SLC5A2 (0.43) | SLC5A1SLC5A2 | |
| SCHEMBL7063823 | 0.72 | SLC5A2 (0.51) | SLC5A1SLC5A2 | |
| SCHEMBL4663151 | 0.70 | SLC5A2 (0.37) | SLC5A1SLC5A2 | |
| SCHEMBL6514723 | 0.70 | SLC5A2 (0.38) | SLC5A1SLC5A2 | |
| SCHEMBL6510862 | 0.70 | SLC5A2 (0.43) | SLC5A1SLC5A2 | |
| SCHEMBL9235203 | 0.70 | SLC1A3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888487-B2 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20100029919-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20060128635-A1 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1550668-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029919-A1 | PYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATE IN PRODUCING THE SAME | SLC2A3, SLC2A1, SLC5A1 | SLC5A1 3/4885SLC5A2 7/4885 |
| US-20060128635-A1 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same | SLC2A3, SLC2A1, SLC5A1 | SLC5A1 3/4885SLC5A2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.