SCHEMBL12677697

SCHEMBL12677697

c1ccc(N(c2ccccc2)c2ccc(COCc3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.61
ALDH1A1 P00352 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
MAPT P10636 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
LYPLA1 O75608 1/20 0.41
LYPLA2 O95372 1/20 0.41
CRHBP P24387 1/20 0.41
ATM Q13315 1/20 0.41
CRHR2 Q13324 1/20 0.41
TLR9 Q9NR96 1/20 0.41
TACR1 P25103 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14773282 0.90 TSHR (0.50) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL14011205 0.90 TSHR (0.48) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL279511 0.90 TSHR (0.48) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL24131104 0.89 TSHR (0.54) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL25976362 0.88 MEN1 (0.47) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL13681215 0.86 TSHR (0.45) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL13681258 0.86 TSHR (0.45) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL14727177 0.86 TSHR (0.45) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL439837 0.85 MEN1 (0.49) TSHRALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL279513 0.85 MEN1 (0.49) TSHRALDH1A1L3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed