Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268619 | 1.00 | ATM (0.40) | ATMNR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL3964124 | 1.00 | ATM (0.40) | ATMNR1H2CYP1A2POLBCYP3A4 | |
| SCHEMBL1724522 | 0.88 | NR1H2 (0.41) | NR1H2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL12213318 | 0.88 | NR1H2 (0.41) | NR1H2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL12204166 | 0.88 | NR1H2 (0.41) | NR1H2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL14117916 | 0.86 | ATM (0.45) | ATMNR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL12213289 | 0.85 | NR1H2 (0.41) | NR1H2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL8065917 | 0.85 | NR1H2 (0.48) | NR1H2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL2526553 | 0.85 | NR1H2 (0.41) | NR1H2CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL3725714 | 0.85 | NR1H2 (0.48) | NR1H2CYP1A2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879852-B2 | such as (4S)-1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-4-[(4,4-dimethylcyclohexyl)(2,2-dimethylpropanoyl)amino]-N,N-dimethyl-L-prolineamide, used for the treatment of obesity, diabetes, inflammation and erectile dysfunction | LG LIFE SCIENCES LTD. (KR) | 2011-02-01 | — | — | US | disclosed |
| US-20090298829-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298829-A1 | MELANOCORTIN RECEPTOR AGONISTS | MC1R, MC3R, MC5R | ATM 4772/4885NR1H2 476/4885CYP1A2 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.