Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 15/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 9/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.50 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11902074 | 0.93 | PIK3CD (0.50) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11901137 | 0.90 | PIK3CD (0.51) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11900814 | 0.90 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11900722 | 0.90 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11902034 | 0.89 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11902030 | 0.89 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11901464 | 0.88 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11901940 | 0.88 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11901335 | 0.88 | PIK3CD (0.56) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA | |
| SCHEMBL11901362 | 0.87 | PIK3CD (0.47) | PIK3CDPIK3CGPIK3R1PIK3CBPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012107465-A1 | HETEROCYCLIC COMPOUNDS AS PI3 KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-08-16 | — | — | WO | disclosed |