SCHEMBL1268355

SCHEMBL1268355

[CH2]C(Br)C(=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16196001 0.79
SCHEMBL1415223 0.75 SMN1; SMN2 (0.48)
SCHEMBL2007852 0.75
SCHEMBL167934 0.75 SMN1; SMN2 (0.48)
SCHEMBL690839 0.75 SMN1; SMN2 (0.48)
SCHEMBL17068140 0.75 SMN1; SMN2 (0.48)
SCHEMBL127462 0.73
SCHEMBL36713 0.73
SCHEMBL2322217 0.73
SCHEMBL28861475 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2079844-B1 SYNTHESIS OF INIMERS AND HYPERBRANCHED POLYMERS UNIV AKRON (US) 2015-01-07 EP disclosed
US-8524942-B2 Synthesis of inimers and hyperbranched polymers THE UNIVERSITY OF AKRON (US) 2013-09-03 US disclosed
US-20110046334-A1 SYNTHESIS OF INIMERS AND HYPERBRANCHED POLYMERS THE UNIVERSITY OF AKRON (US) 2011-02-24 US disclosed
EP-2079844-A1 SYNTHESIS OF INIMERS AND HYPERBRANCHED POLYMERS The University of Akron (US) 2009-07-22 EP disclosed
WO-2008045299-A1 SYNTHESIS OF INIMERS AND HYPERBRANCHED POLYMERS UNIVERSITY OF AKRON (US) 2008-04-17 WO disclosed
US-6455697-B2 Substituted phenyluracils BAYER AKTIENGESELLSCHAFT (DE) 2002-09-24 US disclosed
CN-1090623-C 3-aryl-1, 2, 4-triazole derivatives having herbicidal properties BAYER AG (DE) 2002-09-11 CN disclosed
CN-1325848-A Herbicidal 3-aryl-1,2,4-triazole derivative BAYER AG (DE) 2001-12-12 CN disclosed
EP-0843667-B1 SUBSTITUTED PHENYLURACILS BAYER AG (DE) 2001-10-17 EP disclosed
US-6251828-B1 HERBICIDE FOR TOTAL CONTROL OF WEEDS BAYER AKTIENGESELLSCHAFT (DE) 2001-06-26 US disclosed
US-20010003732-A1 1-(4-cyano-2-fluoro-5-(2-chloro-2-methoxycarbonylethyl) -phenyl)-3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1-(2H)-pyrimidine, for example; use as herbicides; chemical intermediates and method of synthesis ANDREE ROLAND (DE) 2001-06-14 US disclosed
EP-0843667-A1 SUBSTITUTED PHENYLURACILS BAYER AG (DE) 1998-05-27 EP disclosed
CN-1175249-A 3-aryl-1, 2, 4-triazole derivatives having herbicidal properties BAYER AG (DE) 1998-03-04 CN disclosed
WO-1997005118-A1 SUBSTITUTED PHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-13 WO disclosed