Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.55 |
| ▸ | PARP1 | P09874 | 5/20 | 0.34 |
| ▸ | CDC7 | O00311 | 2/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2756437 | 0.94 | SCN10A (0.61) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL1592500 | 0.94 | SCN10A (0.61) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL1592503 | 0.94 | SCN10A (0.61) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL3265964 | 0.94 | SCN10A (0.61) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL15458266 | 0.88 | SCN10A (0.53) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL15457856 | 0.87 | SCN10A (0.52) | SCN10APARP1CDC7CCNE1CDK2 | |
| SCHEMBL240766 | 0.87 | SCN10A (0.71) | SCN10AALDH1A1LMNAMAPTHTT | |
| SCHEMBL18653106 | 0.84 | SCN10A (0.49) | SCN10ACDC7CCNE1CDK2ROCK1 | |
| SCHEMBL1983260 | 0.82 | SCN10A (0.47) | SCN10A | |
| SCHEMBL1982269 | 0.82 | SCN10A (0.47) | SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692346-B1 | An antiviral 1-phenyl-2,5-dibenzimidazol-5-yl-pyrrolidine derivative | ABBVIE BAHAMAS LTD (BS) | 2015-12-02 | — | — | EP | disclosed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012051361-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-04-19 | — | — | WO | disclosed |