⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120700 | 0.74 | — | — | |
| SCHEMBL9390073 | 0.63 | — | — | |
| SCHEMBL2217205 | 0.60 | — | — | |
| SCHEMBL7196707 | 0.60 | — | — | |
| SCHEMBL7476353 | 0.58 | — | — | |
| SCHEMBL1268975 | 0.56 | — | — | |
| SCHEMBL9382008 | 0.56 | — | — | |
| SCHEMBL2265241 | 0.55 | — | — | |
| SCHEMBL29741132 | 0.55 | — | — | |
| SCHEMBL16629066 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987025-B | Crystal form of pralidoxime chloride and preparation method thereof | 成都瑞尔医药科技有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-116987025-A | Crystal form of pralidoxime chloride and preparation method thereof | 成都瑞尔医药科技有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116987025-B | Crystal form of pralidoxime chloride and preparation method thereof | 成都瑞尔医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-116987025-A | Crystal form of pralidoxime chloride and preparation method thereof | 成都瑞尔医药科技有限公司 | 2023-11-03 | — | — | CN | disclosed |
| US-8377972-B2 | Use of quaternary pyridinium compounds for vasoprotection and/or hepatoprotection | Trigendo Sp. zo.o. (PL) | 2013-02-19 | — | — | US | disclosed |
| US-20110118316-A1 | Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection | TRIGENDO SP. Z O.O. (PL) | 2011-05-19 | — | — | US | disclosed |
| US-7893095-B2 | Treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury; 1,4-dimethylpyridinium Chloride; diabetes, metabolic syndrome, atherosclerosis | TRIGENDO SP. Z O.O. (PL) | 2011-02-22 | — | — | US | disclosed |
| US-20080221172-A1 | Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection | TRIGENDO SP. Z O.O. | 2008-09-11 | — | — | US | disclosed |