Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 20/20 | 0.66 |
| ▸ | PIM1 | P11309 | 19/20 | 0.66 |
| ▸ | PIM3 | Q86V86 | 19/20 | 0.66 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12080164 | 0.95 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12079144 | 0.95 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12687530 | 0.93 | PIM1 (0.70) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12080846 | 0.89 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12092796 | 0.89 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12079398 | 0.89 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12080677 | 0.89 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12081162 | 0.89 | PIM1 (0.72) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12079100 | 0.88 | PIM1 (0.76) | PIM2PIM1PIM3GSK3BPRKCQ | |
| SCHEMBL12080093 | 0.88 | PIM1 (0.76) | PIM2PIM1PIM3GSK3BPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120415-A1 | TETRASUBSTITUTED CYCLOHEXYL COMPOUNDS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-09-13 | — | — | WO | disclosed |