Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 20/20 | 0.62 |
| ▸ | PIM3 | Q86V86 | 20/20 | 0.62 |
| ▸ | PIM2 | Q9P1W9 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15592871 | 0.94 | PIM1 (0.62) | PIM1PIM3PIM2 | |
| SCHEMBL15592961 | 0.90 | PIM2 (0.63) | PIM1PIM3PIM2 | |
| SCHEMBL12080175 | 0.88 | PIM2 (0.56) | PIM1PIM3PIM2 | |
| SCHEMBL15592873 | 0.88 | PIM1 (0.64) | PIM1PIM3PIM2 | |
| SCHEMBL15592955 | 0.87 | PIM1 (0.62) | PIM1PIM3PIM2 | |
| SCHEMBL15592867 | 0.83 | PIM1 (0.64) | PIM1PIM3PIM2 | |
| SCHEMBL15592874 | 0.83 | PIM1 (0.65) | PIM1PIM3PIM2 | |
| SCHEMBL15592954 | 0.83 | PIM1 (0.63) | PIM1PIM3PIM2 | |
| SCHEMBL12079637 | 0.82 | PIM1 (0.55) | PIM1PIM3PIM2 | |
| SCHEMBL15592960 | 0.82 | PIM1 (0.64) | PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120415-A1 | TETRASUBSTITUTED CYCLOHEXYL COMPOUNDS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-09-13 | — | — | WO | disclosed |