⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758664 | 0.68 | — | — | |
| SCHEMBL10901122 | 0.67 | — | — | |
| SCHEMBL11134690 | 0.67 | — | — | |
| Tromethamine SCHEMBL8848636 | 0.67 | — | — | |
| SCHEMBL4401544 | 0.64 | — | — | |
| SCHEMBL524127 | 0.64 | — | — | |
| SCHEMBL81841 | 0.64 | — | — | |
| SCHEMBL9001637 | 0.62 | — | — | |
| SCHEMBL4923511 | 0.61 | — | — | |
| SCHEMBL9190103 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879267-B2 | A surface film of contact lense having the controlled thickness and uniformity; coating a molding surface with a high molecular weight polymer, dispensing a blends of a hydrogel and a polysiloxane, curing | J&J VISION CARE, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| EP-1412154-B1 | METHOD FOR IN-MOLD COATING HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE (US) | 2007-04-04 | — | — | EP | disclosed |
| EP-1412154-A1 | METHOD FOR IN-MOLD COATING HYDROGEL ARTICLES | Johson & Johnson Vision Care Inc. (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030052424-A1 | A surface film of contact lense having the controlled thickness and uniformity; coating a molding surface with a high molecular weight polymer, dispensing a blends of a hydrogel and a polysiloxane, curing | JOHNSON & JOHNSON VISION CARE, INC. | 2003-03-20 | — | — | US | disclosed |
| WO-2003011551-A1 | METHOD FOR IN MOLD COATING HYDROGEL ARTICLES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2003-02-13 | — | — | WO | disclosed |