SCHEMBL1269129

SCHEMBL1269129

CC(=CCc1cc(O)c(C)c(C)c1O)CCCC(C)CCCC(C)CCCC(C)C

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.50
PTGS1 P23219 1/20 0.49
PDE4A P27815 1/20 0.49
SNCA P37840 1/20 0.49
PDE3A Q14432 1/20 0.49
TRPV1 Q8NER1 1/20 0.39
PTPN2 P17706 1/20 0.38
CDC25B P30305 1/20 0.38
PSEN1 P49768 2/20 0.35
KDM1A O60341 1/20 0.35
OSBP P22059 1/20 0.34
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269133 1.00 PTPN1 (0.50) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL14283772 0.95 PTGS1 (0.42) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL2138794 0.87 PTPN1 (0.50) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL7048351 0.84 PTPN1 (0.51) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL7077134 0.84 PTPN1 (0.51) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL3503968 0.82 PTPN1 (0.50) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL30598383 0.82 PTPN1 (0.50) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL3503970 0.82 PTPN1 (0.50) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL7143550 0.82 PTPN1 (0.52) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL31312522 0.82 PTGS1 (0.52) PTPN1PTGS1PDE4ASNCAPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110179523-A1 Method for Producing a Transgenic Plant Cell, a Plant or a Part Thereof with Increased Resistance Biotic Stress BASF PLANT SCIENCE GMBH (DE) 2011-07-21 US claimed
EP-2344644-A1 METHOD FOR PRODUCING A TRANSGENIC PLANT CELL, A PLANT OR A PART THEREOF WITH INCREASED RESISTANCE BIOTIC STRESS BASF Plant Science GmbH (DE) 2011-07-20 EP claimed
WO-2010037714-A1 METHOD FOR PRODUCING A TRANSGENIC PLANT CELL, A PLANT OR A PART THEREOF WITH INCREASED RESISTANCE BIOTIC STRESS BASF PLANT SCIENCE GMBH (DE) 2010-04-08 WO claimed
US-20100071091-A1 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2010-03-18 US claimed
EP-1641930-A4 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2008-06-11 EP claimed
EP-1915452-A2 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF Plant Science GmbH (DE) 2008-04-30 EP claimed
EP-1615998-A4 PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2007-06-13 EP claimed
WO-2007020198-A2 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2007-02-22 WO claimed
EP-1641930-A2 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF Plant Science GmbH (DE) 2006-04-05 EP claimed
EP-1615998-A2 PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF Plant Science GmbH (DE) 2006-01-18 EP claimed
WO-2004092349-A2 PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2004-10-28 WO claimed
WO-2004092398-A2 NUCLEIC ACID SEQUENCES ENCODING PROTEINS ASSOCIATED WITH ABIOTIC STRESS RESPONSE AND PLANT CELLS AND PLANTS WITH INCREASED TOLERANCE TO ENVIRONMENTAL STRESS BASF PLANT SCIENCE GMBH (DE) 2004-10-28 WO claimed
EP-3502703-A1 METHOD FOR THE ASSESSMENT OF NAFLD Metanomics Health GmbH (DE) 2019-06-26 EP disclosed
US-8952217-B2 Process for decreasing verbascose in a plant by expression of a chloroplast-targeted fimD protein METANOMICS GMBH (DE) 2015-02-10 US disclosed
US-20140325709-A1 PROCESS FOR THE PRODUCTION OF FINE CHEMICALS METANOMICS GMBH (DE) 2014-10-30 US disclosed
EP-2674496-A2 Nucleic acid sequences encoding proteins associated with abiotic stress response and plant cells and plants with increased tolerance to environmental stress BASF Plant Science GmbH (DE) 2013-12-18 EP disclosed
WO-2000008169-A1 DNA SEQUENCE CODING FOR A 1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE AND THE OVERPRODUCTION THEREOF IN PLANTS SUNGENE GMBH & CO.KGAA (DE) 2000-02-17 WO disclosed
EP-0531639-B1 Tocopherol cyclase HOFFMANN LA ROCHE (CH) 1999-09-01 EP disclosed
US-5432069-A Tocopherol cyclase isolated from Chlorella protothecoides, Dunaliella salina and wheat leaves HOFFMANN-LA ROCHE INC. (US) 1995-07-11 US disclosed
EP-0531639-A2 Tocopherol cyclase F. HOFFMANN-LA ROCHE AG (CH) 1993-03-17 EP disclosed