SCHEMBL1269155

SCHEMBL1269155

[CH2]OC(Cl)(Cl)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL787873 0.69
SCHEMBL11788167 0.64
SCHEMBL7093988 0.64
SCHEMBL3800774 0.64
SCHEMBL1149080 0.62
SCHEMBL18423815 0.62
SCHEMBL1817629 0.62
SCHEMBL9366184 0.62
SCHEMBL11243169 0.60
SCHEMBL11174465 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010128516-A2 PROCESS FOR THE PREPARATION OF FLIBANSERIN INVOLVING NOVEL INTERMEDIATES SYMED LABS LIMITED (IN) 2010-11-11 WO claimed
EP-0690856-A4 UNIV NEW YORK (US) 1996-02-07 EP claimed
EP-0690856-A1 ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1996-01-10 EP claimed
EP-0681568-A1 PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND $g(b)-LACTAM INTERMEDIATES THEREFOR THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1995-11-15 EP claimed
WO-1994022856-A1 ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 1994-10-13 WO claimed
WO-1994018164-A1 PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND β-LACTAM INTERMEDIATES THEREFOR THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1994-08-18 WO claimed
EP-0428376-A1 Method for preparation of taxol using an oxazinone FLORIDA STATE UNIVERSITY (US) 1991-05-22 EP claimed
EP-0400971-A2 Method for preparation of taxol FLORIDA STATE UNIVERSITY (US) 1990-12-05 EP claimed
EP-4387954-A1 LONG-LIVED REDOX-ACTIVE MOLECULES WITH LOW REDOX POTENTIAL President and Fellows of Harvard College (US) 2024-06-26 EP disclosed
WO-2024130218-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
WO-2024130217-A1 STAPLED PEPTIDES AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2024-06-20 WO disclosed
CN-118185235-A Curable composition, method for producing cured product, and cured product thereof 株式会社ADEKA 2024-06-14 CN disclosed
CN-108884298-B Curable composition, method for producing cured product, and cured product thereof 株式会社ADEKA 2024-05-31 CN disclosed
EP-4355334-A1 USE OF ATR INHIBITORS IN COMBINATION WITH PARP INHIBITORS FOR TREATING CANCER Repare Therapeutics Inc. (CA) 2024-04-24 EP disclosed
WO-1996000708-A1 METHOD FOR PREPARING ALKYLATING AGENTS AND THEIR USE FOR ALKYLATING CYCLIC UREAS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-01-11 WO disclosed
EP-0682660-A4 1995-12-20 EP disclosed
EP-0682660-A1 SYNTHESIS OF TAXOL, ANALOGS AND INTERMEDIATES WITH VARIABLE A-RING SIDE CHAINS BRYN MAWR COLLEGE (US) 1995-11-22 EP disclosed
US-5385897-A 3-(3-quaternary ammonium prop-1-enyl), 7-((2-(aminothiazol-4-yl), 2-(alkoxyimino)acetamido)-3-isocephems; penicillin-resistant staphylococcus ROUSSEL-UCLAF (FR) 1995-01-31 US disclosed
WO-1994018186-A1 SYNTHESIS OF TAXOL, ANALOGS AND INTERMEDIATES WITH VARIABLE A-RING SIDE CHAINS BRYN MAWR COLLEGE (US) 1994-08-18 WO disclosed
US-5278332-A Derivatives of cyclohexane PERSTORP AB (SE) 1994-01-11 US disclosed