⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29845742 | 1.00 | — | — | |
| SCHEMBL30240679 | 0.72 | — | — | |
| SCHEMBL31484874 | 0.72 | CCR1 (0.48) | — | |
| SCHEMBL29370280 | 0.72 | — | — | |
| SCHEMBL3297307 | 0.72 | — | — | |
| SCHEMBL17669536 | 0.72 | CCR1 (0.48) | — | |
| SCHEMBL30935767 | 0.72 | DYRK1A (0.63) | — | |
| SCHEMBL4402187 | 0.72 | DYRK1A (0.63) | — | |
| SCHEMBL43935 | 0.72 | — | — | |
| SCHEMBL13261852 | 0.71 | DYRK1A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190071441-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-03-07 | — | — | US | claimed |
| US-10174025-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-08 | — | — | US | claimed |
| US-20180099964-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-04-12 | — | — | US | claimed |
| US-9902723-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-02-27 | — | — | US | claimed |
| US-9879009-B2 | Pyrazole derivative manufacturing method | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2018-01-30 | — | — | US | claimed |
| CN-107074845-A | The manufacture method of pyrazole derivatives | 持田制药株式会社 | 2017-08-18 | — | — | CN | claimed |
| US-20170217958-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | claimed |
| US-20170210740-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-27 | — | — | US | claimed |
| EP-3176168-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | Mochida Pharmaceutical Co., Ltd. (JP) | 2017-06-07 | — | — | EP | claimed |
| EP-3176167-A1 | PYRAZOLE DERIVATIVE MANUFACTURING METHOD | Mochida Pharmaceutical Co., Ltd. (JP) | 2017-06-07 | — | — | EP | claimed |
| US-20250333399-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KHORA SPV 1 LLC (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250325548-A1 | TUMOR SUPPRESSOR P73 TRANSCRIPTIONALLY REGULATES C-FLIP TO IMPEDE ITS PRIMING OF EXTRINSIC APOPTOSIS WHILE AN EXAMPLE SWITCHER COMPOUND CB-7587351 DEGRADES C-FLIP PROTEIN | UNIV BROWN (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250304576-A1 | IKK INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2025-10-02 | — | — | US | disclosed |
| US-12331039-B2 | Inhibitors of fibroblast growth factor receptor kinases | KHORA SPV 1, LLC (US) | 2025-06-17 | — | — | US | disclosed |
| US-12331058-B2 | SHP2 and CDK4/6 dual-target inhibitory compound and pharmaceutical composition containing the same | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2025-06-17 | — | — | US | disclosed |
| US-20030187026-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-10-02 | — | — | US | disclosed |
| WO-2003051366-A2 | 3-(PHENYL-ALKOXY)-5-(PHENYL)-PYRIDINE DERIVATIVES AND RELATED COMPOUNDS AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER | ABBOTT LABORATORIES (US) | 2003-06-26 | — | — | WO | disclosed |
| EP-1161431-A4 | 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2002-04-24 | — | — | EP | disclosed |
| EP-1161431-A1 | 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053602-A1 | 6-AZAINDOLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 2000-09-14 | — | — | WO | disclosed |