Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14406555 | 0.90 | PIK3CA (0.54) | PIK3CAPIK3CD | |
| SCHEMBL1485494 | 0.89 | PIK3CA (0.56) | PIK3CAPIK3CD | |
| SCHEMBL12693239 | 0.89 | PIK3CD (0.58) | PIK3CAPIK3CD | |
| SCHEMBL12689013 | 0.84 | PIK3CA (0.56) | PIK3CAPIK3CD | |
| SCHEMBL1485362 | 0.83 | PIK3CA (0.54) | PIK3CAPIK3CD | |
| SCHEMBL11967479 | 0.82 | PIK3CA (0.64) | PIK3CAPIK3CD | |
| SCHEMBL1485206 | 0.81 | PIK3CD (0.51) | PIK3CAPIK3CD | |
| SCHEMBL14406548 | 0.79 | PIK3CD (0.56) | PIK3CAPIK3CD | |
| SCHEMBL1485158 | 0.78 | PIK3CD (0.58) | PIK3CAPIK3CD | |
| SCHEMBL12689395 | 0.78 | PIK3CD (0.52) | PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120244149-A1 | BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | BLAQUIERE NICOLE (US) | 2012-09-27 | — | — | US | disclosed |
| US-20110076292-A1 | BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2011-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120244149-A1 | BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | BMX, PIK3CA, PI4KA | PIK3CA 2/4885PIK3CD 7/4885 |
| US-20110076292-A1 | BENZOXAZEPIN PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | BMX, PIK3CA, PI4KA | PIK3CA 2/4885PIK3CD 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.