Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1026405 | 0.84 | AGPAT2 (0.42) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL12690187 | 0.84 | KDM4E (0.43) | AGPAT2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL1024981 | 0.82 | AGPAT2 (0.38) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1022966 | 0.82 | AGPAT2 (0.38) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1025657 | 0.81 | AGPAT2 (0.40) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1026539 | 0.80 | AGPAT2 (0.47) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1023531 | 0.79 | AGPAT2 (0.39) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1024908 | 0.79 | CNR2 (0.41) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1147120 | 0.78 | AGPAT2 (0.39) | AGPAT2HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL1025825 | 0.78 | AGPAT2 (0.41) | AGPAT2HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445522-B2 | Substituted 2-(4-pyridyl)benzoxazoles, and compositions thereof, for use in arthropod pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-21 | — | — | US | disclosed |
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245167-A1 | ARTHROPOD PEST CONTROL METHOD AND COMPOSITION | C5, C1S, C1R | AGPAT2 652/4885HDAC6 1809/4885HDAC3 866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.