SCHEMBL1269596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12793245	0.90	POLB (0.88)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL7955587	0.85	POLB (0.73)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL12793258	0.85	POLB (1.00)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL28072234	0.83	POLB (0.76)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL12793250	0.83	POLB (0.96)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL8871272	0.83	POLB (0.76)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL12793270	0.83	POLB (0.96)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL1268829	0.82	USP2 (0.76)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL3342226	0.81	POLB (0.73)	POLBLMNASMN1; SMN2KMT2AMEN1
	SCHEMBL2769910	0.81	POLB (0.73)	POLBLMNASMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.