Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127006 | 0.91 | BRS3 (0.33) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL15588770 | 0.91 | BRS3 (0.33) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL9607182 | 0.91 | BRS3 (0.33) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL15589037 | 0.91 | BRS3 (0.33) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL1725546 | 0.91 | BRS3 (0.33) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL15588834 | 0.89 | GAA (0.35) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL15588715 | 0.89 | GAA (0.35) | KMT2AMEN1GAAHTTRAB9A | |
| SCHEMBL4127520 | 0.88 | GAA (0.32) | KMT2AMEN1GAAHTT | |
| SCHEMBL2839969 | 0.88 | GAA (0.32) | KMT2AMEN1GAAHTT | |
| SCHEMBL15589272 | 0.88 | GAA (0.32) | KMT2AMEN1GAAHTTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012120428-A1 | NOVEL KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-09-13 | — | — | WO | disclosed |