Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 19/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563474 | 0.91 | PDE2A (0.51) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12603911 | 0.86 | PDE2A (0.46) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL1987338 | 0.86 | PDE2A (0.46) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12604757 | 0.85 | PDE2A (0.41) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12604739 | 0.84 | CYP1A2 (0.43) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12603620 | 0.83 | PDE2A (0.43) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12563476 | 0.83 | PDE2A (0.49) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12605025 | 0.82 | HDAC1 (0.44) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12605032 | 0.82 | HDAC1 (0.57) | PDE2AHDAC1HDAC8HDAC6 | |
| SCHEMBL12563512 | 0.82 | PDE2A (0.48) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307394-B1 | SULPHONAMIDES AS VANILLOID RECEPTOR ANTAGONIST | AMOREPACIFIC CORP (KR) | 2012-09-26 | — | — | EP | disclosed |