Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 19/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984584 | 1.00 | PDE2A (0.42) | PDE2A | |
| SCHEMBL12697558 | 0.92 | TRPV1 (0.39) | PDE2A | |
| SCHEMBL1987158 | 0.92 | TRPV1 (0.39) | PDE2A | |
| SCHEMBL1987338 | 0.92 | PDE2A (0.46) | PDE2A | |
| SCHEMBL12603911 | 0.92 | PDE2A (0.46) | PDE2A | |
| SCHEMBL12604733 | 0.91 | PDE2A (0.42) | PDE2A | |
| SCHEMBL1989719 | 0.91 | PDE2A (0.42) | PDE2A | |
| SCHEMBL12603914 | 0.88 | PDE2A (0.40) | PDE2A | |
| SCHEMBL1989466 | 0.88 | PDE2A (0.40) | PDE2A | |
| SCHEMBL12697479 | 0.87 | HDAC1 (0.38) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307394-B1 | SULPHONAMIDES AS VANILLOID RECEPTOR ANTAGONIST | AMOREPACIFIC CORP (KR) | 2012-09-26 | — | — | EP | disclosed |
| WO-2010002209-A2 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2010-01-07 | — | — | WO | disclosed |