⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006909 | 0.70 | — | — | |
| SCHEMBL720480 | 0.70 | — | — | |
| SCHEMBL652953 | 0.70 | — | — | |
| SCHEMBL8708711 | 0.70 | — | — | |
| SCHEMBL3321852 | 0.68 | — | — | |
| SCHEMBL11260080 | 0.68 | — | — | |
| SCHEMBL3321855 | 0.68 | — | — | |
| SCHEMBL1570075 | 0.68 | — | — | |
| SCHEMBL10427686 | 0.67 | — | — | |
| SCHEMBL10427707 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400551-B1 | Polyamide chains of precise length and their conjugates with proteins | AMYLIN PHARMACEUTICALS INC (US) | 2007-06-13 | — | — | EP | claimed |
| US-20050025740-A1 | Polyoxime compounds and their preparation | AMYLIN PHARMACEUTICALS, INC. | 2005-02-03 | — | — | US | claimed |
| US-6663869-B1 | Linkages between polypeptide organic molecules are oxime linkages formed by reaction of a keto, aldehyde or amino-oxy group on the amino acid | GRYPHON THERAPEUTICS, INC. | 2003-12-16 | — | — | US | claimed |
| US-6174530-B1 | Homogeneous polyoxime compositions and their preparation by parallel assembly | GRYPHON SCIENCES | 2001-01-16 | — | — | US | claimed |
| EP-0697891-B1 | POLYOXIME COMPOUNDS AND THEIR PREPARATION | ROSE KEITH (CH) | 2000-03-29 | — | — | EP | claimed |
| US-6001364-A | COMPRISING A BASEPLATE STRUCTURE HAVING A PLURALITY OF OXIME BONDS, WHEREIN EACH OXIME BOND LINKS A SPECIFICALLY ACTIVE MOLECULE TO THE BASEPLATE; FOR INDUCING AN IMMUNE RESPONSE IN AN ANIMAL | GRYPHON SCIENCES (US) | 1999-12-14 | — | — | US | claimed |
| EP-0697891-A1 | POLYOXIME COMPOUNDS AND THEIR PREPARATION | Rose, Keith (CH) | 1996-02-28 | — | — | EP | claimed |
| WO-1994025071-A1 | POLYOXIME COMPOUNDS AND THEIR PREPARATION | ROSE KEITH (CH) | 1994-11-10 | — | — | WO | claimed |
| EP-0448513-A2 | Process for production of peptidylglycine alpha-hydroxylating monooxygenase and use thereof | Japat Ltd (CH) | 1991-09-25 | — | — | EP | claimed |
| US-20110124556-A1 | Insulin and IGF-1 Receptor Agonists and Antagonists | NOVO NORDISK A/S (DK) | 2011-05-26 | — | — | US | disclosed |
| US-20110039779-A1 | IGF-1R BINDING PROTEINS AND ANTAGONISTS | OSTERGAARD SOREN | 2011-02-17 | — | — | US | disclosed |
| CN-101802001-A | Igf-1r binding proteins and antagonists | ANTYRA INC | 2010-08-11 | — | — | CN | disclosed |
| US-20090192072-A1 | Insulin and IGF-1 Receptor Agonists and Antagonists | NOVO NORDISK A/S (DK) | 2009-07-30 | — | — | US | disclosed |
| US-20090053807-A1 | Insulin and IGF-1 Receptor Agonists and Antagonists | NOVO NORDISK A/S (DK) | 2009-02-26 | — | — | US | disclosed |
| EP-0378456-B1 | TETRALIN DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0448513-A2 | Process for production of peptidylglycine alpha-hydroxylating monooxygenase and use thereof | Japat Ltd (CH) | 1991-09-25 | — | — | EP | disclosed |
| US-5041673-A | Aminopeptidase inhibitors, immunomodulators, analgesics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |
| CN-1044460-A | Novel 1,2,3,4-tetralin derivative | MERRELL DOW PHARMA (US) | 1990-08-08 | — | — | CN | disclosed |
| EP-0378456-A1 | Tetralin derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-07-18 | — | — | EP | disclosed |