⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128203 | 0.83 | — | — | |
| SCHEMBL128864 | 0.81 | PPARG (0.46) | — | |
| SCHEMBL131191 | 0.80 | — | — | |
| SCHEMBL5077214 | 0.79 | PPARG (0.48) | — | |
| SCHEMBL27389163 | 0.79 | PPARG (0.48) | — | |
| SCHEMBL7019850 | 0.78 | — | — | |
| SCHEMBL160882 | 0.78 | — | — | |
| SCHEMBL11264421 | 0.78 | — | — | |
| SCHEMBL160884 | 0.78 | — | — | |
| SCHEMBL6466416 | 0.76 | CES1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106147562-A | Polyurethane modified organic silicon polyurethane type marine anti-fouling coating material preparation method of | 西安文利电子科技有限责任公司 | 2016-11-23 | — | — | CN | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| EP-2943584-B1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KK (JP) | 2019-08-14 | — | — | EP | disclosed |
| US-10041937-B2 | Macrophage identification agent, and identification method, sorting method, evaluation method, screening method and kit using the macrophage identifier agent | CANON KABUSHIKI KAISHA (JP) | 2018-08-07 | — | — | US | disclosed |
| CN-106147562-A | Polyurethane modified organic silicon polyurethane type marine anti-fouling coating material preparation method of | 西安文利电子科技有限责任公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20160018389-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2016-01-21 | — | — | US | disclosed |
| EP-2943584-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | Canon Kabushiki Kaisha (JP) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014192972-A1 | MACROPHAGE IDENTIFICATION AGENT, AND IDENTIFICATION METHOD, SORTING METHOD, EVALUATION METHOD, SCREENING METHOD AND KIT USING THE MACROPHAGE IDENTIFIER AGENT | CANON KABUSHIKI KAISHA (JP) | 2014-12-04 | — | — | WO | disclosed |
| US-8450319-B2 | Pyrrolopyridazinone compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-28 | — | — | US | disclosed |
| EP-1982986-B1 | PYRROLOPYRIDAZINONE COMPOUND AS PDE4 INHIBITOR | UBE INDUSTRIES (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20090036453-A1 | Pyrrolopyridazinone Compound | UBE INDUSTRIES, LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1982986-A1 | PYRROLOPYRIDAZINONE COMPOUND | Ube Industries, Ltd. (JP) | 2008-10-22 | — | — | EP | disclosed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | disclosed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | disclosed |
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |