⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786685 | 1.00 | — | — | |
| SCHEMBL18515639 | 1.00 | — | — | |
| SCHEMBL11223318 | 0.84 | — | — | |
| SCHEMBL4960195 | 0.82 | — | — | |
| SCHEMBL20118837 | 0.80 | KMT2A (0.37) | — | |
| SCHEMBL15081511 | 0.77 | TLR4 (0.35) | — | |
| SCHEMBL14845605 | 0.77 | TLR4 (0.35) | — | |
| SCHEMBL18289470 | 0.71 | SRD5A1 (0.43) | — | |
| SCHEMBL24861121 | 0.70 | — | — | |
| SCHEMBL4849281 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107641094-B | Application of alkaloid compound 5-hydroxypyrrolidine-2-ketone in preparation of anticomplement drugs | 石河子大学 | 2020-02-07 | — | — | CN | claimed |
| EP-0705240-A1 | NOVEL PROCESSES FOR PREPARING (S)-4-AMINO-HEPTA-5,6-DIENOIC ACID AND INTERMEDIATES THEREOF | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | claimed |
| WO-1995000470-A1 | NOVEL PROCESSES FOR PREPARING (S)-4-AMINO-HEPTA-5,6-DIENOIC ACID AND INTERMEDIATES THEREOF | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | claimed |
| US-12479799-B2 | Bioconjugation reagent and methods | UNIVERSITEIT GENT (BE) | 2025-11-25 | — | — | US | disclosed |
| US-20230365514-A1 | MACROCYCLIC COMPOUNDS | NOVO NORDISK RESEARCH CENTRE OXFORD LIMITED (GB) | 2023-11-16 | — | — | US | disclosed |
| EP-3746452-B1 | STEREOSELECTIVE SYNTHESIS AND PROCESS FOR THE MANUFACTURING OF 2'-DEOXYNUCLEOSIDES | US HEALTH (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-4122597-A2 | A PROCESS FOR PRODUCING A DIISOCYANATE PRODUCT, A PROCESS FOR PRODUCING AN AROMATIC ISOCYANATE PRODUCT AND A PROCESS FOR PRODUCING A POLYURETHANE PRODUCT | Novomer, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022265043-A1 | COMPOUND AND LABELED BIOMATERIAL USING SAME | 富士フイルム株式会社 | 2022-12-22 | — | — | WO | disclosed |
| CN-115304587-A | Preparation method of afatinib impurity | 北京康派森医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| US-20220169604-A1 | BIOCONJUGATION REAGENT AND METHODS | UNIVERSITEIT GENT (BE) | 2022-06-02 | — | — | US | disclosed |
| US-4882350-A | TREATMENT OF INTELLECTUAL OR NERVOUS ASTHENIAS, MEMORY FAILURES | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| US-4829079-A | AMNESIA | ROUSSEL UCLAF (FR) | 1989-05-09 | — | — | US | disclosed |
| EP-0298818-A1 | 1-Benzenesulfonyl 2-oxo 5-alkylthio pyrrolidines, process for their preparation, their intermediaries and their use as medicines | ROUSSEL-UCLAF (FR) | 1989-01-11 | — | — | EP | disclosed |
| EP-0296979-A2 | 1-Benzoyl-2-oxo-5-alkoxy-pyrrolidine derivatives, their preparation, their use and preparations containing them | ROUSSEL-UCLAF (FR) | 1988-12-28 | — | — | EP | disclosed |
| EP-0296978-A2 | 1-Benzyl 2-oxo 5-alkoxy pyrrolidine derivatives, process for their preparation, compositions containing them and their use in medicines | ROUSSEL-UCLAF (FR) | 1988-12-28 | — | — | EP | disclosed |
| EP-0134481-B1 | GAMMA-ALLENYL-GAMMA-AMINOBUTYRIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1987-12-16 | — | — | EP | disclosed |
| EP-0229566-A2 | 1-Benzene sulfonyl 2-oxo-5-alkoxy pyrrolidines, process for their preparation, their use as medicine and compositions containing them | ROUSSEL-UCLAF (FR) | 1987-07-22 | — | — | EP | disclosed |
| US-4668703-A | ENZYME INHIBITORS, INFECTIONS, PARASITICIDES | SYNTEX (U.S.A.) INC. (US) | 1987-05-26 | — | — | US | disclosed |
| EP-0134481-A1 | Gamma-allenyl-gamma-aminobutyric acids | SYNTEX (U.S.A.) INC. (US) | 1985-03-20 | — | — | EP | disclosed |