Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16002956 | 0.90 | FOLH1 (0.47) | FOLH1PRMT1PTPN1PRMT5CARM1 | |
| SCHEMBL25489625 | 0.89 | FOLH1 (0.50) | FOLH1PRMT1PTPN1PRMT5CARM1 | |
| SCHEMBL2057092 | 0.88 | FOLH1 (0.48) | FOLH1PRMT1PTPN1PRMT5CARM1 | |
| SCHEMBL2057097 | 0.88 | FOLH1 (0.48) | FOLH1PRMT1PTPN1PRMT5CARM1 | |
| SCHEMBL13813755 | 0.88 | FOLH1 (0.42) | FOLH1PRMT1PTPN1PRMT5CARM1 | |
| SCHEMBL16000425 | 0.87 | FOLH1 (0.46) | FOLH1PRMT1PTPN1PRMT5CARM1 | |
| SCHEMBL12713684 | 0.86 | PRMT1 (0.51) | FOLH1PRMT1PTPN1HTR1AFOLR1 | |
| SCHEMBL16940687 | 0.85 | PRMT1 (0.51) | FOLH1PRMT1PTPN1HTR1AFOLR1 | |
| SCHEMBL12713861 | 0.85 | PRMT1 (0.51) | FOLH1PRMT1PTPN1HTR1AFOLR1 | |
| SCHEMBL24842484 | 0.85 | PRMT1 (0.51) | FOLH1PRMT1PTPN1HTR1AFOLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248832-A1 | Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy | UNIV EMORY (US) | 2023-08-10 | — | — | US | disclosed |
| US-20160310604-A1 | SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY | CEDARS-SINAI MEDICAL CENTER | 2016-10-27 | — | — | US | disclosed |
| US-20110085974-A1 | SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY | CEDARS-SINAI MEDICAL CENTER (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160310604-A1 | SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY | SELL, EPCAM, SELPLG | FOLH1 41/4885PRMT1 2454/4885PTPN1 1336/4885 |
| US-20230248832-A1 | Small Molecule Ligand-Drug Conjugates for Targeted Cancer Therapy | SELL, EPCAM, SELPLG | FOLH1 41/4885PRMT1 2454/4885PTPN1 1336/4885 |
| US-20110085974-A1 | SMALL MOLECULE LIGAND-DRUG CONJUGATES FOR TARGETED CANCER THERAPY | SELL, EPCAM, SELPLG | FOLH1 41/4885PRMT1 2454/4885PTPN1 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.