SCHEMBL12714636

SCHEMBL12714636

C=N/N=C(\NN)NC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.37
TAS2R38 P59533 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19604212 0.78 GAA (0.30)
SCHEMBL10122906 0.66
SCHEMBL7745 0.63
SCHEMBL29707140 0.63
SCHEMBL208969 0.63
SCHEMBL28117108 0.63 KDM4E (0.50) CRBNTAS2R38
SCHEMBL24420703 0.63 CRBN (0.43) CRBNTAS2R38
SCHEMBL19413892 0.63
SCHEMBL14048896 0.61
Hydrochloric Acid SCHEMBL4326471 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2305684-A1 Poycyloalkylpurines as adenosine receptor antagonists Biogen Idec MA Inc. (US) 2011-04-06 EP disclosed