Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 3/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 5/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240807 | 0.98 | GBA1 (0.41) | GLB1GBA2GBA1GUSBEPHX1 | |
| SCHEMBL12166786 | 0.82 | CA1 (0.43) | GLB1GBA2GBA1FUCA1LSS | |
| SCHEMBL12166921 | 0.82 | CYP1A2 (0.34) | GLB1GBA2GBA1FUCA1NOS3 | |
| SCHEMBL24822394 | 0.77 | TBXA2R (0.35) | TBXA2RPTGFRPTGER2ALDH1A1 | |
| SCHEMBL13587934 | 0.77 | — | — | |
| SCHEMBL12166681 | 0.77 | CYP1A2 (0.37) | GLB1GBA2GBA1FUCA1 | |
| SCHEMBL8749490 | 0.76 | GLB1 (0.44) | GLB1GBA2GBA1 | |
| SCHEMBL14138536 | 0.76 | GAA (0.31) | EPHX1 | |
| SCHEMBL14294568 | 0.76 | MGAM (0.30) | GBA1 | |
| SCHEMBL3693371 | 0.76 | GAA (0.31) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308495-A1 | Method and composition for treating peripheral vascular diseases | Sucampo AG (CH) | 2011-04-13 | — | — | EP | disclosed |