Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821305 | 1.00 | PDE2A (0.34) | PDE2APARP1TP53NOTUMHCRTR2 | |
| SCHEMBL13586393 | 0.90 | TP53 (0.33) | PDE2ATP53NOTUMHCRTR2 | |
| SCHEMBL12223929 | 0.88 | SERPINE1 (0.33) | PDE2ATP53 | |
| SCHEMBL12823069 | 0.88 | CYP19A1 (0.37) | PDE2ATP53NOTUMHCRTR2 | |
| SCHEMBL13586224 | 0.88 | CYP19A1 (0.37) | PDE2ATP53NOTUMHCRTR2 | |
| SCHEMBL12823048 | 0.87 | PDE2A (0.32) | PDE2ATP53 | |
| SCHEMBL12821309 | 0.87 | PDE2A (0.32) | PDE2ATP53 | |
| SCHEMBL12823444 | 0.86 | PDE2A (0.31) | PDE2A | |
| SCHEMBL12823257 | 0.86 | PDE2A (0.31) | PDE2A | |
| SCHEMBL12823915 | 0.86 | PDE2A (0.32) | PDE2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305627-A1 | TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-04-06 | — | — | EP | disclosed |