Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 11/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641968 | 0.87 | F2R (0.51) | F2RCNR1TMEM97 | |
| SCHEMBL13808366 | 0.83 | F2R (0.58) | F2RCNR1TMEM97RORCSCN9A | |
| SCHEMBL13808322 | 0.83 | F2R (0.53) | F2RCNR1TMEM97RORC | |
| SCHEMBL13808314 | 0.82 | F2R (0.51) | F2RCNR1TMEM97RORCSCN9A | |
| SCHEMBL13808374 | 0.81 | F2R (0.56) | F2RCNR1TMEM97RORCSCN9A | |
| SCHEMBL642712 | 0.79 | F2R (0.55) | F2RCNR1TMEM97 | |
| SCHEMBL642761 | 0.79 | F2R (0.55) | F2RCNR1TMEM97CYP3A4 | |
| SCHEMBL12720366 | 0.79 | F2R (0.53) | F2RCNR1TMEM97RORCSCN9A | |
| SCHEMBL13808094 | 0.78 | F2R (0.52) | F2RCNR1TMEM97USP30SCN9A | |
| SCHEMBL27798031 | 0.78 | F2R (0.52) | F2RCYP3A4RORCSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |