Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 10/20 | 0.42 |
| ▸ | FASN | P49327 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12720304 | 0.91 | F2R (0.39) | F2RFASNCNR1TMEM97HSD11B1 | |
| SCHEMBL13808094 | 0.88 | F2R (0.52) | F2RFASNCNR1TMEM97P2RY14 | |
| SCHEMBL13808106 | 0.88 | F2R (0.44) | F2RFASNCNR1TMEM97LIPE | |
| SCHEMBL12720052 | 0.85 | F2R (0.49) | F2RFASNCNR1TMEM97 | |
| SCHEMBL10234373 | 0.84 | F2R (0.46) | F2RFASNCNR1TMEM97HSD11B1 | |
| SCHEMBL13808280 | 0.83 | F2R (0.48) | F2RFASNCNR1TMEM97HSD11B1 | |
| SCHEMBL12720065 | 0.83 | F2R (0.47) | F2RCNR1TMEM97HSD11B1LIPE | |
| SCHEMBL13808129 | 0.83 | F2R (0.41) | F2RCNR1TMEM97PROKR1 | |
| SCHEMBL12720610 | 0.81 | F2R (0.39) | F2RFASNCNR1TMEM97LIPE | |
| SCHEMBL13050750 | 0.81 | F2R (0.47) | F2RCNR1TMEM97HSD11B1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |