Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 7/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12719989 | 0.87 | F2R (0.47) | F2RCNR1TMEM97EPHX2 | |
| SCHEMBL12720467 | 0.87 | F2R (0.59) | F2RCNR1TMEM97EPHX2PREP | |
| SCHEMBL12719997 | 0.85 | F2R (0.46) | F2RCNR1TMEM97EPHX2EPHX1 | |
| SCHEMBL12720296 | 0.84 | F2R (0.42) | F2RHRH3LIPE | |
| SCHEMBL642165 | 0.80 | F2R (0.60) | F2RCNR1TMEM97EPHX2FAAH | |
| SCHEMBL12720025 | 0.79 | F2R (0.49) | F2RCNR1TMEM97EPHX2FAAH | |
| SCHEMBL641260 | 0.78 | F2R (0.67) | F2RCNR1TMEM97EPHX2PREP | |
| SCHEMBL641261 | 0.78 | F2R (0.69) | F2RCNR1TMEM97EPHX2PREP | |
| SCHEMBL640933 | 0.77 | F2R (0.65) | F2RCNR1TMEM97EPHX2PREP | |
| SCHEMBL12720334 | 0.77 | F2R (0.50) | F2RCNR1TMEM97EPHX2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |