Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14343539 | 0.89 | HSD17B10 (0.49) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL1272381 | 0.88 | HSD17B10 (0.42) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL1271995 | 0.88 | HSD17B10 (0.42) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL30700635 | 0.86 | NR1H2 (0.42) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL1273232 | 0.85 | HSD17B10 (0.41) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL1273344 | 0.85 | HSD17B10 (0.41) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL1272276 | 0.82 | HSD17B10 (0.39) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL25625816 | 0.80 | MC4R (0.40) | HSD17B10NPC1SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL24106710 | 0.78 | MEN1 (0.41) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL5423413 | 0.77 | HSD17B10 (0.61) | HSD17B10NPC1SMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | BIRC5, XIAP, BIRC2 | HSD17B10 3459/4885NPC1 1601/4885SMN1; SMN2 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.