Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727491 | 1.00 | P2RY12 (0.41) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL12727441 | 0.93 | P2RY12 (0.40) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL1640123 | 0.91 | P2RY12 (0.52) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL1640124 | 0.91 | P2RY12 (0.52) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL1640638 | 0.91 | P2RY12 (0.52) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL1640671 | 0.90 | P2RY12 (0.48) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL12727415 | 0.88 | P2RY12 (0.42) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL12727433 | 0.87 | P2RY12 (0.42) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL12768891 | 0.85 | P2RY12 (0.44) | P2RY12TP53MAPTHTR3ARXFP1 | |
| SCHEMBL1640630 | 0.84 | P2RY12 (0.51) | P2RY12TP53MAPTHTR3ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098247-A1 | Substituted Dihydroquinazolines as Platelet ADP Receptor Inhibitors | PORTOLA PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098247-A1 | Substituted Dihydroquinazolines as Platelet ADP Receptor Inhibitors | TBXA2R, F2R, PTGER1 | P2RY12 120/4885TP53 3875/4885MAPT 4611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.