Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 20/20 | 0.72 |
| ▸ | BIRC2 | Q13490 | 14/20 | 0.72 |
| ▸ | BIRC3 | Q13489 | 7/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272986 | 1.00 | XIAP (0.72) | XIAPBIRC2BIRC3 | |
| SCHEMBL1273582 | 0.95 | XIAP (0.71) | XIAPBIRC2BIRC3 | |
| SCHEMBL1273671 | 0.94 | XIAP (0.74) | XIAPBIRC2BIRC3 | |
| SCHEMBL1274133 | 0.93 | XIAP (0.70) | XIAPBIRC2BIRC3 | |
| SCHEMBL1273616 | 0.93 | XIAP (0.72) | XIAPBIRC2BIRC3 | |
| SCHEMBL1273737 | 0.93 | XIAP (0.73) | XIAPBIRC2BIRC3 | |
| SCHEMBL1273105 | 0.92 | XIAP (0.69) | XIAPBIRC2BIRC3 | |
| SCHEMBL1272963 | 0.92 | XIAP (0.70) | XIAPBIRC2BIRC3 | |
| SCHEMBL12874578 | 0.92 | XIAP (0.74) | XIAPBIRC2BIRC3 | |
| SCHEMBL1274048 | 0.91 | XIAP (0.71) | XIAPBIRC2BIRC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034469-A1 | Heterocyclic Compound | BIRC5, XIAP, BIRC2 | XIAP 2/4885BIRC2 3/4885BIRC3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.